Tag Archives: future technology

Why Ethereum Might Have More Value Than Bitcoin (In The Long Run)

Ethereum 2.0 Deposit Contract Surpasses $25 Billion Worth of ETH | Finance  Magnates

Nobody can predict the future. As someone who often talks about the future and future technology, I like to belabor that. It’s an important disclaimer because if the future were that easy to predict, then there would be no need for lotteries, fantsy sports, or the stock market.

It’s like my old political science professor once told me in college. Nobody knows anything. He said that in the context of a lesson about politics, but I think it also applies to many other fields. Technology, economics, and finance are definitely among them.

I’m certainly no expert in any of those fields. I like writing and telling sexy stories about technology. I’m not the least bit qualified to make informed predictions about it or any related subjects. I’m not dumb, but my expertise is limited to comics, sexy short stories, and football stats.

Having gotten that out of the way, I’d like to give a brief layman’s opinion about cryptocurrencies. I know that’s a chaotic subject, at the moment. The recent rise of multiple cryptocurrencies has made headlines, albeit for absurd reasons at times. However, I think it’s safe to say that this is not another passing internet fad in the mold of planking.

This technology has real value.

This technology is changing the world.

This technology will likely continue to evolve and improve with time.

I say this as someone who has followed the news surrounding cryptocurrencies for years. I also say that as someone who recently purchased his first stash of Bitcoins. As of this moment, I only have a few hundred bucks in my Bitcoin wallet. I’ve also seen the value fluctuate significantly. I’ve even had a chance to spend them, which was surprisingly smooth.

After this experience, I wouldn’t call myself a full-fledged Bitcoin enthusiast. I’m not planning to invest all my money into Bitcoins anytime soon. However, I genuinely believe this technology has great value. I also believe it’ll become an integral part of our future, with respect to finance and the economy.

At the same time, I can’t help but note its limits. I’ve even highlighted a few of them before. Bitcoin has many benefits, but I think its value is somewhat skewed because it just happens to be the biggest in terms of market cap, as well as the most well-known cryptocurrency.

When most people think cryptocurrencies, the first thing they think of is Bitcoin. That gives it a huge benefit over other cryptocurrencies, of which there are many. That benefit is likely to fuel its value for years to come.

However, having used it and followed the growth of cryptocurrencies more closely in recent years, I do not believe it’s the most valuable cryptocurrency on the market. I also don’t think that Bitcoin, in its current form, will succeed beyond a certain point.

Many people compare Bitcoin to digital gold and I think that’s a fairly apt comparison. Bitcoin, like real gold, is mostly a store of value. That’s what it was designed to be and, for the most part, it fulfills that purpose well. A bar of gold and a stash of Bitcoins will function in primarily the same way.

In terms of value and utility, though, that’s where I think Bitcoin falls short. Even gold has more uses beyond being a store of value. I think if cryptocurrencies are to achieve more than just functioning as digital money, they need to do more.

For that reason, I believe Ethereum, the second-most popular cryptocurrency in terms of market value, may have more value in the long run. It’s not a meme currency like Dogecoin. The technology behind Ethereum actually makes use of the features that have made Bitcoin so valuable.

For those not familiar with Ethereum, it’s a cryptocurrency that’s similar to Bitcoin in many ways. It also uses blockchain technology to create a digital store of value. It has been operating since 2015 and has grown considerably in recent years. What sets it apart, though, is its ability to be programmed.

Whereas Bitcoin is mostly raw math and data, Ethereum is more like an operating system or a programming language. With it, users can create smart contracts, which are essentially digital contracts that are self-enforcing. That means no middleman or lawyers are needed to enforce a signed agreement.

For anyone who has ever had to deal with lawyers or contracts, it’s hard to overstate the value of such a feature. Since many contracts already involve money, Ethereum essentially tightens that connection. In the same way Bitcoin allows people to be their own bank, Ethereum allows them to be their own legal team.

In a world that has only become more connected and digitized, especially after a global pandemic, there’s considerable utility in that. I would argue that utility will make Ethereum more useful than Bitcoin in the long run.

That’s not to say it’ll eventually usurp Bitcoin or all other cryptocurrencies. I think Bitcoin will always benefit from the first, as well as the most well-known. I just think that benefit will only take it so far. Gold is useful, but it’s not nearly as useful as electricity, oil, or even steel. Those assets have tangible, measurable utility. Ethereum offers that on top of being a store of value.

Now, at the moment, smart contracts and other programs run on Ethereum aren’t exactly mainstream. That’s to be expected. This technology is still relatively new. People aren’t quite sure what to do with it yet.

Then again, the same could’ve been said back in the mid-2000s when smartphones came out. It took a while for developers and entrepreneurs to create the kinds of applications that would go onto make billions. It wasn’t just one app or one use. The phones were just a platform. The value came once people started building things atop that foundation.

With Bitcoin, there’s not much of a foundation. Its only app is as a store of value. That’s akin to a flip-phone, which can only make phone calls and store numbers. Granted, even flip phones still have utility, but they’ll never be able to do what a basic smartphone can do.

I don’t pretend to know what sort of applications or programs Ethereum could help create. It’ll probably take more than one for it to truly show its value. I also don’t pretend to know when those sorts of applications or programs will come along. The potential is there. It’s up to people far smarter and more ambitious than most of us to realize it.

I could still be dead wrong about this. Given the malleable nature of cryptocurrencies, it may be the case that Bitcoin eventually gains the same function as Ethereum. For all I know, an entirely new cryptocurrency could emerge that’s better and more valuable than any created to date. That’s entirely possible. Like I said, nobody knows anything about what the future will hold. We just know we’re creating some incredibly valuable tools with cryptocurrencies. We just haven’t figured out how to maximize their value. One day, we will and we’ll all be richer because of it.

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Filed under Bitcoin, Cryptocurrency, futurism, technology

The Promise, Perils, And Potential Of Elon Musk’s New Tesla Worker Robots

Tesla Promised a Robot. Was It Just a Recruiting Pitch? | WIRED

We’ve all had jobs that are laborious, boring, and repetitive. In fact, for most of human history, those were pretty much the only jobs there were. If you didn’t spend 12 hours a day in a field or factory, doing the same thing again and again, you didn’t have what you needed to survive. Only royalty and the wealthy got to enjoy leisure of any kind.

These days, those types of jobs are still there. Even though we live in an age of increasing automation, there are still plenty of jobs that are hard, repetitive, and draining. Anyone who works in an Amazon warehouse can attest to this.

I have some personal experience with those jobs. I once worked a job at a fast-food restaurant that probably could’ve been done by a trained monkey. I hated it and wouldn’t want my children having to do that kind of work. The fact that many people still have to work these jobs to make endsmeat is tragic.

The prospect of eliminating these jobs with technology, robotics, and artificial intelligence has always been intriguing. I’ve written about it before, both the artificial intelligent aspect of it and the social implications. Unlike other ideas about the future or future technology, this is one trend that’s already happening. Automation is a real thing and it’s not stopping anytime soon.

However, Elon Musk is once again looking to make another massive leap and enrich himself even more in the process. In addition to working on electric cars, commercial space flight, brain/computer interfaces, and flamethrowers, he now wants to create a legion of humanoid robot workers.

Basically, he wants to create the robots in “I, Robot,” minus the part where they go haywire and try to kill everyone. I wish I could say that was a joke, but we already have killer drones, so I think that would be in poor taste.

Musk made an official announcement of this effort on behalf of Tesla. Below is an excerpt of the story, courtesy of The Verge.

The Verge: Elon Musk says Tesla is working on humanoid robots

Tesla CEO Elon Musk says his company is working on a humanoid robot and that it will build a prototype “sometime next year.” The humanoid robot will leverage Tesla’s experience with automated machines in its factories, as well as some of the hardware and software that powers the company’s Autopilot driver assistance software.

Musk, who has spoken repeatedly about his fears of runaway artificial intelligence, said the Tesla Bot is “intended to be friendly,” but that the company is designing the machine at a “mechanical level” so that “you can run away from it, and most likely overpower it.” It will be five feet, eight inches tall, weigh 125 pounds, and have a screen for a face. The code name for the bot inside the company is “Optimus,” he said.

The robots will be designed to handle “tasks that are unsafe, repetitive or boring,” the company’s website reads, but little else, at least at first. (There, the bot is simply called “Tesla Bot.”) “I think essentially in the future, physical work will be a choice, if you want to do it you can,” Musk said.

Musk revealed drawings of the robot near the tail end of his company’s “AI Day” event, where it showcased some of the artificial intelligence and supercomputer technologies that it’s working on with the goal of one day powering self-driving cars. The company also had a mannequin version on the stage, which wasn’t working.

Now, before I continue, I want to make a quick disclaimer. I am not about to gush over Elon Musk and anoint him the bringer of a new techno-utopia. He might be one of the world’s richest human beings, but even he has limitations. I know I’ve gushed over Elon Musk in the past, but I’ve since tempered some of my attitudes.

I’m aware that Musk has a reputation of overpromising and failing to deliver. The article even points that out. I’m also aware that Musk, like many billionaires, has done some shady things in the past. You really can’t get as rich and successful as him without being an asshole to some extent.

At the same time, you cannot overlook the man’s success. He didn’t invent the electric car any more than Steve Jobs invented the personal computer or the smartphone. He just took existing technology, combined it into a new product, and successfully marketed it in a way no other human being had done to that point. He was so good at it that he became even richer than he already was.

Like it or not, he succeeded. He thinks big and tries to deliver. Even when he fails, he gets people to push the envelope. He underestimated just how difficult it was to create a self-driving car. I have a feeling he’ll do the same with these robots.

However, I also think that he will do more than anyone to speed up the ongoing trends in automation. Like I said before, this is not some new, fanciful technology. Robots exist. They already work in factories, doing work that used to be done by humans. They aren’t humanoid, but that’s because they’re limited to just a single task.

These humanoid robots will offer something different. They’ll be able to perform a wider ranger of tasks. The robots that make cares can’t be reconfigured to make something else. These Tesla bots could at least begin that process. Even if it’s flawed and unsuccessful at first, that’s still progress. Pretty much all technological advances are like that in the beginning.

His timing here might actually be just right. In recent years, companies like Boston Dynamics have shown off just how capable robots have become. They’re no T-1000, but they’re getting to a point where they can walk, run, lift, and jump as well as an ordinary human. With some refinement, they’ll be able to do even more.

Just like he did with the electric car, Musk could create the first true fleet of robot workers. They wouldn’t be able to replace every human working a laborious job, but they would be able to take the place of some. At a time when there’s a growing labor shortage, there’s definitely going to be a market for that sort of thing.

Personally, I don’t think Musk is going to be able to deliver functional robot workers as quickly as he claims. However, I do think he’ll get the ball rolling for a new industry. He’ll demonstrate that this technology is possible and there’s a growing market for it. In the same way other companies have started making electric cars, they’ll also start making robot workers.

Even if he only succeeds in part, though, that does raise some major concerns. Stories about workers being exploited aren’t difficult to find and the COVID-19 pandemic only made those stories more relevant. I don’t doubt for a second that if companies could replace their workforce with robots and get the same production, they would do so in a heartbeat.

I suspect that some are already cheering Musk on behind the scenes. Those same people probably won’t give much thought to the larger implications of a robot workforce. The prospect of a large population of people who aren’t working, have no job prospects, and are unable to earn a proper living does not bode well for society.

While people like Musk have advocated for a universal basic income of sorts, the politics behind that are messy to say the least. Given how politics rarely seems to keep up with technology, it’s unreasonable to expect it to be ready for a robot workforce that does all the laborious jobs that people used to do. It’s definitely cause for concern. In that sense, perhaps it’s a good thing that what Musk seeks to do probably won’t work exceptionally well, at least at first. However, even if he fails, it’s only a matter of time and engineering before someone else succeeds. At that point, we won’t be able to avoid the larger implications.

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Why We Should Embrace Synthetic Meat (As Soon As Possible)

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If you’re reading this, then there’s a good chance you drank milk at some point this year. You probably drank a lot more of it when you were a kid. The fact that you’re reading this proves that you didn’t die, as a result. That may not seem like a big deal, but compared to 100 years ago, it counts as a noteworthy feat.

Between 1850 and 1950, approximately a half-million infants died due to diseases contracted by drinking milk. If you do the math, that’s about 5,000 deaths a year, just from drinking milk. Keep in mind, these are children. That’s a lot of death and suffering for drinking one of the most basic substances the animal kingdom.

These days, death by drinking milk is exceedingly rare. Thanks to processes like pasteurization, milk is one of the safest substances you can drink. If anyone does get sick, it’s usually from drinking raw or unpasteurized milk. However, it’s so rare that most people don’t think about it. It’s just a normal part of how we manage our food and nourish ourselves.

I bring up milk because it nicely demonstrates what happens when we apply technology to improve the quality, safety, and abundance of our food. Despite what certain misguided critics may say, many of which probably haven’t experienced extreme starvation, this has been an objective good for humanity, civilization, and the world, as a whole.

Modern medicine and the Green Revolution, championed by the likes of Norman Borlaug, helped give us more efficient ways of producing massive quantities of food. Now, there’s another technological advancement brewing that might end up being more impactful. You’ve probably seen commercials for it already. It has many names, but for now, I’m just going to call it synthetic meat.

It’s almost exactly what it sounds like. It’s the process of producing meat through artificial processes, none of which involve the slaughtering of animals. For those concerned about animal welfare and environmental impacts, it’s the ultimate solution. At most, the animals contribute a few cells. The rest is grown in a laboratory. Nobody has to get hurt. Nobody has to go vegan, either.

It seems too good to be true and there are certainly aspects of synthetic meats that are overhyped. However, unlike other advancements like Neuralink or nanobots, this is already an evolving market. The first synthetic burger was made and consumed in 2013. It was the culmination of a long, laborious effort that cost upwards of $300,000.

Those costs soon came down and they came down considerably. By 2017, the cost of that same meat patty was around $11. People have paid much more for expensive caviar. That’s impressive progress for something that’s still a maturing technology with many unresolved challenges. With major fast food companies getting in on the game, the technology is likely to progress even more.

It’s here where I want to make an important point about this technology. Regardless of how you feel about it or why it’s being developed, there’s one aspect to it that’s worth belaboring.

We should embrace synthetic meat.

In fact, we should embrace this technology faster than others because the benefits of doing so will only compound.

I say this as someone who has tried an impossible meat burger. It’s not terrible. I wouldn’t mind eating them regularly if they were the only option available. That said, you can still tell it’s not traditional beef. That’s because this meat isn’t exactly the kind of cultured meat that’s grown in a lab. It’s assembled from plant proteins and various other well-known substances.

Ideally, synthetic meat wouldn’t just be indistinguishable from traditional beef. It would actually be safer than anything you could get naturally. Meat grown in a lab under controlled conditions can ensure it’s free of food-born illnesses, which are still a problem with meat production. It can also more effectively remove harmful byproducts, like trans fats.

In theory, it might also be possible to produce meat with more nutrients. Imagine a burger that’s as healthy as a bowl of kale. Picture a T-bone steak that has the same amount of nutrients as a plate of fresh vegetables. That’s not possible to do through natural means, but in a lab where the meat is cultured at the cellular level, it’s simply a matter of chemistry and palatability.

Meat like that wouldn’t just be good for our collective health. It would be good for both the environment and the economy, two issues that are rarely aligned. Even if you don’t care at all about animal welfare, synthetic meats has the potential to produce more product with less resources. On a planet of over 7.6 billion, that’s not just beneficial. It’s critical.

At the moment, approximately 70 percent of the agricultural land in the world is dedicated to the meat production. In terms of raw energy requirements, meat requires considerably more energy than plants. That includes water consumption, as well. Making meat in its current form requires a lot of resources and with a growing population, the math is working against us.

Say what you want about vegetarians and vegans when they rant about the meat industry. From a math and resources standpoint, they have a point. However, getting rid of meat altogether just isn’t feasible. It tastes too good and it has too many benefits. We can’t make people hate the taste of burgers, but we can improve the processes on how those burgers are made.

Instead of industrial farms where animals are raised in cramped quarters, pumped full of hormones, and raised to be slaughtered, we could have factories that produce only the best quality meat from the best animal cells. It wouldn’t require vast fields or huge quantities of feed. It would just need electricity, cells, and the assorted cellular nutrients.

Perhaps 3D printing advances to a point where specific cuts of meat could be produced the same way we produce specific parts for a car. Aside from producing meat without having to care for than slaughter animals, such a system would be able to increase the overall supply with a smaller overall footprint.

Needing less land to produce meat means more land for environmental preservation or economic development. Farming, both for crops and for meat, is a major contributor to deforestation. Being able to do more with less helps improve how we utilize resources, in general. Even greedy corporations, of which the food industry has plenty, will improve their margins by utilizing this technology.

Increased supply also means cheaper prices and if the taste is indistinguishable from traditional meat, then most people are going to go with it, regardless of how they feel about it. There will still be a market for traditional, farm-raised meats from animals, just as there’s a market for non-GMO foods. However, as we saw with the Green Revolution in the early 20th century, economics tends to win out in the long run.

It’s a promising future for many reasons. There are many more I could list relating to helping the environment, combating starvation, and improving nutrition. Alone, they’re all valid reasons to embrace this technology and seek greater improvements. If I had to pick only one, though, it’s this.

If we don’t develop this technology, then these delicious meats that we love could be exceedingly scarce or prohibitively expensive in the future.

Like I said earlier, the way we currently produce meat is grossly inefficient. At some point, the demand for meat is going to exceed the current system’s capacity to produce it in an economical way. At that point, this delicious food that we take for granted might not be so readily available and the substitutes might not be nearly as appetizing.

The issue becomes even more pressing if we wish to become a space-faring civilization, which will be necessary at some point. If we still want to enjoy burgers, chicken wings, and bacon at that point, we’ll need to know how to make it without the vast fields and facilities we currently use. Otherwise, we might be stuck dining on potatoes like Matt Damon in “The Martian.”

While the situation isn’t currently that urgent, this is one instance where a new technology is the extra push. You don’t have to be a major investor in companies like Beyond Meat or Impossible Foods. Just go out of your way to try one of these new synthetic meat products. Let the market know that there’s demand for it and the machinations of capitalism will do the rest.

I understand that our inner Ron Swanson will always have a craving for old fashioned burgers, steaks, and bacon. Those things don’t have to go away completely, just as traditional farming hasn’t gone away completely. However, when a particular technology already exists and has so many potential benefits, it’s worth pursuing with extra vigor.

The planet will benefit.

The people will benefit.

The animals will benefit.

Our society, as a whole, will benefit.

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Filed under biotechnology, CRISPR, Current Events, Environment, futurism, health, technology

What Keeps Bitcoin From Being A (Bigger) Part Of Our Future

I consider myself an enthusiast of technology. On many occasions, I’ve wildly speculated about emerging technology and expressed unapologetic excitement about certain trends. In general, I have the utmost respect and support for those who share this passion. I don’t always agree with their outlook or speculation, but I get where they’re coming from.

Then, there are Bitcoin enthusiasts. I’ll just come out and say I have mixed feelings about them.

Don’t get me wrong. I don’t want to diminish what a remarkable technology Bitcoin is. It is a complicated and, at times, confusing technology. Even the Wikipedia page only does so much to explain what it is, where it came from, and why it matters. That’s not surprising. There was plenty of confusion about the internet too when it first emerged.

While I don’t consider myself an enthusiast, Bitcoin has sparked my curiosity. I do sometimes look into major news stories and developments surrounding the technology. The fact that it has lasted over a decade and made some people legitimate millionaires is proof enough that Bitcoin has real, tangible value. Those who keep saying that Bitcoin is just a fad or will crash are becoming increasingly scarce.

I’m convinced that Bitcoin, and other cryptocurrencies like it, are here to stay. They’ve proven that they have value in an increasingly digital landscape. As the internet becomes more prevalent and accessible, their role will only grow. That being said, I’m not yet convinced Bitcoin’s role will go beyond a certain point.

Those who say Bitcoin is the future of money are likely talking in hyperbole.

Those who say Bitcoin and the blockchain are the most revolutionary technologies since email are also likely exaggerating.

I don’t doubt for a second that these people believe in what they’re saying. I just haven’t seen enough to warrant that kind of enthusiasm. The issue isn’t as much about the merits of the technology as it is about how it’s being used. I’m not just referring to its role in the illegal drug trade, either.

At the moment, Bitcoin is fairly accessible. If you have a smartphone and an internet connection, you can download a simple wallet for free. If you do a quick search for a Bitcoin ATM, you can purchase Bitcoins with the same ease you would when purchasing a gift card. It’s what you do after that where the issues arise.

What exactly can you buy with Bitcoin that you can’t buy more easily through other means? That’s not me being facetious. This is where I tend to diverge with Bitcoin enthusiasts. I understand that some major ecommerce sites accept Bitcoin, namely Overstock. I’m also aware that more and more retailers are accepting Bitcoin.

However, the only ones taking advantage of that option are those who go out of their way to use Bitcoin. For most people, especially those who aren’t as tech savvy, there just aren’t enough benefits to warrant the extra effort. On top of that, Bitcoin does have some lingering flaws that are hard to work around. Then again, you can say the same thing about traditional money.

None of that even begins to highlight the growing issues associated with mining Bitcoins.

Now, that could change. It’s not a certainty, but it is a possibility. Like any new tech, the issue isn’t always about whether or not it works. Bitcoin clearly works and it’s been working for nearly a decade. It’s whether or not there’s a “killer app” to entice ordinary people to go through the effort of learning about, acquiring, and using Bitcoin.

The problem is that, thanks to incidents like the Silk Road, the primary use of Bitcoin and cryptocurrencies like it have been for the purchase of drugs or other illicit services. Regardless of how you feel about the politics surrounding illegal drugs and services, that’s the reputation Bitcoin has. It’s just a way for criminals and their cohorts to operate.

That’s not a killer app. It’s also not sustainable.

In order for Bitcoin to play a bigger part in our future, it needs to have a good, meaningful use. It took cell phones decades to find that. Just being able to make phone calls, remember phone numbers, and occasionally host a game of solitaire wasn’t enough. Other apps like music, video chatting, and cameras had to get into the mix before the public and the market embraced them.

That’s what Bitcoin needs. I don’t claim to know what that entails. I think Bitcoin has to get to a point where using it is as simple as using a credit card or debit card. It also needs a particular use or product that will justify the physical and financial investment. That use also can’t be illegal. It’s no secret that the internet owes much of its early growth to the porn industry, but porn isn’t illegal.

Bitcoin, in my opinion, will need something bigger than porn. It might also need to wait until more parts of the world are connected to broadband internet. Maybe it involves voting, enforcing contracts, or the development of new peer-to-peer networks, such as Open Bazaar. I don’t know. I’m not smart enough to figure it out at the moment.

In the meantime, I’ll certainly keep an eye on Bitcoin. I don’t deny it has its uses in the current world. It’s just too limited right now. Whether it has a large or small role in the future that awaits us remains to be seen.

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Filed under Bitcoin, futurism, technology

Thought Experiment: When Does Technology Make Us Non-Human?

The following is a video from my YouTube channel, Jack’s World. It explores another thought experiment about technology and how it’s affecting us, as a species. I’ve covered this sort of thing before and the implications. I’m looking to see if there’s an audience for this on my channel. Enjoy!

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Filed under Artificial Intelligence, futurism, human nature, Jack's World, technology, Thought Experiment, YouTube

The First CRISPR Patients Are Living Better: Why That Matters After 2020

It’s been a while since I’ve talked about CRISPR, biotechnology, and the prospect of ordinary people enhancing their biology in ways straight out of a comic book. In my defense, this past year has created plenty of distractions. Some have been so bad that my usual optimism of the future has been seriously damaged.

While my spirit is wounded, I still have hope that science and technology will continue to progress. If anything, it’ll progress with more urgency after this year. A great many fields are bound to get more attention and investment after the damage done by a global pandemic.

We can’t agree on much, but we can at least agree on this. Pandemics are bad for business, bad for people, bad for politics, and just objectively awful for everyone all around, no matter what their station is in life.

There’s a lot of incentive to ensure something like this never happens again is what I’m saying. While we’re still a long way from ending pandemics entirely, we already have tools that can help in that effort. One is CRISPR, a promising tool I’ve talked about in the past. While it wasn’t in a position to help us during this pandemic, research into refining it hasn’t stopped.

Despite all the awful health news of this past year, some new research has brought us some promising results on the CRISPR front. In terms of actually treading real people who have real conditions, those results are in and they give us reason to hope.

One such effort involved using CRISPR to help treat people with Sickle Cell Disease, a genetic condition that hinders the ability of red blood cells to carry oxygen. It affects over 4 million people worldwide and often leads to significant complications that can be fatal.

Since CRISPR is all about tweaking genetics, it’s a perfect mechanism with which to develop new therapies. Multiple patients have undergone experimental treatments that utilize this technology. In a report form NPR, the results are exceeding expectations for all the right reasons.

NPR: First Patients To Get CRISPR Gene-Editing Treatment Continue To Thrive

At a recent meeting of the American Society for Hematology, researchers reported the latest results from the first 10 patients treated via the technique in a research study, including Gray, two other sickle cell patients and seven patients with a related blood disorder, beta thalassemia. The patients now have been followed for between three and 18 months.

All the patients appear to have responded well. The only side effects have been from the intense chemotherapy they’ve had to undergo before getting the billions of edited cells infused into their bodies.

The New England Journal of Medicine published online this month the first peer-reviewed research paper from the study, focusing on Gray and the first beta thalassemia patient who was treated.

“I’m very excited to see these results,” says Jennifer Doudna of the University of California, Berkeley, who shared the Nobel Prize this year for her role in the development of CRISPR. “Patients appear to be cured of their disease, which is simply remarkable.”

Make no mistake. This is objectively good news and not just for people suffering from sickle cell disease.

Whenever new medical advances emerge, there’s often a wide gap between developing new treatments and actually implementing them in a way that makes them as commonplace as getting a prescription. The human body is complex. Every individual’s health is different. Taking a treatment from the lab to a patient is among the biggest challenge in medical research.

This news makes it official. CRISPR has made that leap. The possible treatments aren’t just possibilities anymore. There are real people walking this planet who have received this treatment and are benefiting because of it. Victoria Gray, as referenced in the article, is just one of them.

That’s another critical threshold in the development of new technology. When it goes beyond just managing a condition to helping people thrive, then it becomes more than just a breakthrough. It becomes an opportunity.

It sends a message to doctors, researchers, and biotech companies that this technology works. Some of those amazing possibilities that people like to envision aren’t just dreams anymore. They’re manifesting before our eyes. This is just one part of it. If it works for people with Sickle Cell Disease, what other conditions could it treat?

I doubt I’m the first to ask that question. As I write this, there are people far smarter and more qualified than me using CRISPR to develop a whole host of new treatments. After a year like 2020, everyone is more aware of their health. They’re also more aware of why science and medicine matter. It can do more than just save our lives. It can help us thrive.

We learned many hard lessons in 2020, especially when it comes to our health. Let’s not forget those lessons as we look to the future. This technology is just one of many that could help us prosper in ways not possible in previous years. We cheered those who developed the COVID-19 vaccine. Let’s start cheering those working on new treatments with CRISPR.

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Filed under biotechnology, CRISPR, futurism, health, technology

Why We Should Treat Our Data As (Valuable) Property

Many years ago, I created my first email address before logging into the internet. It was a simple AOL account. I didn’t give it much thought. I didn’t think I was creating anything valuable. At the time, the internet was limited to slow, clunky dial-up that had little to offer in terms of content. I doubt anyone saw what they were doing as creating something of great value.

I still have that email address today in case you’re wondering. I still regularly use it. I imagine a lot of people have an email address they created years ago for one of those early internet companies that used to dominate a very different digital world. They may not even see that address or those early internet experiences as valuable.

Times have changed and not just in terms of pandemics. In fact, times tends to change more rapidly in the digital world than it does in the real world. The data we created on the internet, even in those early days, became much more valuable over time. It served as the foundation on which multi-billion dollar companies were built.

As a result, the data an individual user imparts onto the internet has a great deal of value. You could even argue that the cumulative data of large volumes of internet users is among the most valuable data in the world.

Politicians, police, the military, big businesses, advertising agencies, marketing experts, economists, doctors, and researchers all have use for this data. Many go to great lengths to get it, sometimes through questionable means.

The growing value of this data raises some important questions.

Who exactly owns this data?

How do we go about treating it from a legal, fiscal, and logistical standpoint?

Is this data a form of tangible property, like land, money, or labor?

Is this something we can exchange, trade, or lease?

What is someone’s recourse if they want certain aspects of their data removed, changed, or deleted?

These are all difficult questions that don’t have easy answers. It’s getting to a point where ownership of data was an issue among candidates running for President of the United States. Chances are, as our collective data becomes more vital for major industries, the issue will only grow in importance.

At the moment, it’s difficult to determine how this issue will evolve. In the same way I had no idea how valuable that first email address would be, nobody can possibly know how the internet, society, the economy, and institutions who rely on that data will evolve. The best solution in the near term might not be the same as the best solution in the long term.

Personally, I believe that our data, which includes our email addresses, browsing habits, purchasing habits, and social media posts, should be treated as personal property. Like money, jewels, or land, it has tangible value. We should treat it as such and so should the companies that rely on it.

However, I also understand that there are complications associated with this approach. Unlike money, data isn’t something you can hold in your hand. You can’t easily hand it over to another person, nor can you claim complete ownership of it. To some extent, the data you create on the internet was done with the assistance of the sites you use and your internet service provider.

Those companies could claim some level of ownership of your data. It might even be written in the fine print of those user agreements that nobody ever reads. It’s hard to entirely argue against such a claim. After all, we couldn’t create any of this data without the aid of companies like Verizon, AT&T, Amazon, Apple, Facebook, and Google. At the same time, these companies couldn’t function, let alone profit, without our data.

It’s a difficult question to resolve. It only gets more difficult when you consider laws like the “right to be forgotten.” Many joke that the internet never forgets, but it’s no laughing matter. Peoples’ lives can be ruined, sometimes through no fault of their own. Peoples’ private photos have been hacked and shared without their permission.

In that case, your data does not at all function like property. Even if it’s yours, you can’t always control it or what someone else does with it. You can try to take control of it, but it won’t always work. Even data that was hacked and distributed illegally is still out there and there’s nothing you can do about it.

Despite those complications, I still believe that our data is still the individual’s property to some extent, regardless of what the user agreements of tech companies claim. Those companies provide the tools, but we’re the ones who use them to build something. In the same way a company that makes hammers doesn’t own the buildings they’re used to make, these companies act as the catalyst and not the byproduct.

Protecting our data, both from theft and from exploitation, is every bit as critical as protecting our homes. An intruder into our homes can do a lot of damage. In our increasingly connected world, a nefarious hacker or an unscrupulous tech company can do plenty of damage as well.

However, there’s one more critical reason why I believe individuals need to take ownership of their data. It has less to do with legal jargon and more to do with trends in technology. At some point, we will interact with the internet in ways more intimate than a keyboard and mouse. The technology behind a brain/computer interface is still in its infancy, but it exists and not just on paper.

Between companies like Neuralink and the increasing popularity of augmented reality, the way we interact with technology is bound to get more intimate/invasive. Clicks and link sharing are valuable today. Tomorrow, it could be complex thoughts and feelings. Whoever owns that stands to have a more comprehensive knowledge of the user.

I know it’s common refrain to say that knowledge is power, but when the knowledge goes beyond just our browsing and shopping habits, it’s not an unreasonable statement. As we build more and more of our lives around digital activities, our identities will become more tied to that data. No matter how large or small that portion might be, we’ll want to own it as much as we can.

It only gets more critical if we get to a point where we can fully digitize our minds, as envisioned in shows like “Altered Carbon.” At some point, our bodies are going to break down. We cannot preserve it indefinitely for the same reason we can’t preserve a piece of pizza indefinitely. However, the data that makes up our minds could be salvaged, but that opens the door to many more implications.

While that kind of technology is a long way off, I worry that if we don’t take ownership of our data today, then it’ll only get harder to do so in the future. Even before the internet, information about who we are and what we do was valuable.

This information forms a big part of our identity. If we don’t own that, then what’s to stop someone else from owning us and exploiting that to the utmost? It’s a question that has mostly distressing answers. I still don’t know how we go about staking our claim on our data, but it’s an issue worth confronting. The longerwe put it off, the harder it will get.

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Our Future Robot Overlords Will Now Be Able To Dance (Thanks To Boston Dynamics)

As bad as last year was for so many people, there were some things that 2020 just couldn’t stop. When it comes to technology, a global crisis has a way of hindering certain processes while accelerating others. For many, that meant more telework and reliance on streaming media to stave off boredom.

However, it may very well end up being the case that 2020 proved just how frail human beings and their societies are. It only takes a tiny microscopic virus to send our entire society to a screeching halt. It’s sobering, but it’s probably going to be a source of humor for our future robot overlords.

I tend to be optimistic about the future and technological trends. I’m also somewhat of a pragmatist. I realize that we human beings have a lot of limits. Emerging technology, especially in the field of artificial intelligence, promises to help us transcend those limits.

Right now, it’s still mostly fodder for science fiction writers, futurists, and Elon Musk wannabes. We’re not quite there yet in terms of making a machine that’s as smart as a human. However, we’re probably going to get there faster than skeptics, naysayers, and the general public realize.

It won’t happen overnight. It probably won’t even happen in the span of a single year. When it does happen, though, hindsight will make it painfully obvious that the signs were there. This was bound to happen. We had ample time to prepare for it. Being fallible humans, we could only do so much.

In that sense, I suspect that years from now, we’ll look back on what Boston Dynamics did to close out 2020. This company, who has a history of making robots that look way too advanced to exist outside a Terminator movie, decided to do something with their robots that would leave an indellible mark on the year.

They succeeded by teaching their robots how to dance.

I know it already went viral, but it’s worth posting again. Remember this video and this moment. Chances are it’ll be a major indicator years from now that this is when robots began catching up to humanity in terms of capabilities. At this point, it’ sonly a matter of time before they exceed us.

When that time comes, will we be ready? Will we embrace them while they embrace us?

If they don’t, just know that they will now be able to dance on our graves.

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Big Tech, AI Research, And Ethics Concerns: Why We Should All Worry

In general, I root for technology and technological progress. Overall, I believe it has been a net benefit for humanity. It’s one of the major reasons why we’ve made so much progress as a global society in the past 100 years.

I’ve sung the praises of technology in the past, speculated on its potential, and highlighted individuals who have used it to save millions of lives. For the most part, I focus on the positives and encourage other people to have a less pessimistic view of technology and the change it invites.

That said, there is another side to that coin and I try not to ignore it. Like anything, technology has a dark side. It can be used to harm just as much as it can be used to hurt, if not more so. You could argue that we couldn’t have killed each other at such a staggering rate in World War II without technology.

It’s not hyperbole to say that certain technology could be the death of us all. In fact, we’ve come distressingly close to destroying ourselves before, namely with nuclear weapons. There’s no question that kind of technology is dangerous.

However, artificial intelligence could be far more dangerous than any nuclear bomb. I’ve talked about it before and I’ll likely bring it up again. This technology just has too much potential, for better and for worse.

That’s why when people who are actually researching it have concerns, we should take notice. One such individual spoke out recently, specifically someone who worked for Google, an organization with deep pockets and a keen interest in Artificial Intelligence.

According to a report from the Associated Press, a scholar named Timnit Gebru expressed serious concerns about Google’s AI research, specifically in how their operating ethics. For a company as big and powerful as Google, that’s not a trivial comment. This is what she had to say.

AP News: Google AI researcher’s exit sparks ethics, bias concerns

Prominent artificial intelligence scholar Timnit Gebru helped improve Google’s public image as a company that elevates Black computer scientists and questions harmful uses of AI technology.

But internally, Gebru, a leader in the field of AI ethics, was not shy about voicing doubts about those commitments — until she was pushed out of the company this week in a dispute over a research paper examining the societal dangers of an emerging branch of AI.

Gebru announced on Twitter she was fired. Google told employees she resigned. More than 1,200 Google employees have signed on to an open letter calling the incident “unprecedented research censorship” and faulting the company for racism and defensiveness.

The furor over Gebru’s abrupt departure is the latest incident raising questions about whether Google has strayed so far away from its original “Don’t Be Evil” motto that the company now routinely ousts employees who dare to challenge management. The exit of Gebru, who is Black, also raised further doubts about diversity and inclusion at a company where Black women account for just 1.6% of the workforce.

And it’s exposed concerns beyond Google about whether showy efforts at ethical AI — ranging from a White House executive order this week to ethics review teams set up throughout the tech industry — are of little use when their conclusions might threaten profits or national interests.

I bolded that last sentence because I think it’s the most relevant. It’s also the greatest cause for concern. I suspect Ms. Gebru is more concerned than most because the implications are clear.

When a tool as powerful as advanced AI is developed, who gets to determine how it’s used? Who gets to program the ethical framework by which it operates? Who gets to decide how the benefits are conferred and the harms are reduced?

Moreover, how do you even go about programming an AI with the right kind of ethics?

That’s a very relative question and one we can’t avoid if we’re going to keep developing this technology. I’ve tried to answer it, but I’m hardly an expert. Ms. Gebru was definitely in a better position than me or most other people with a passing interest in this field.

Then, she gets fired and starts expressing concerns publicly. The fact that she can and Google isn’t facing much in terms of repercussions should be concerning. It may also be a sign of the larger challenges we’re facing.

Google, like many other organizations researching advanced AI, is a profit-seeking tech company. They’re not some utopian technocrats. They’re a business who is obligated to make their investors happy. Advanced AI will help them do that, but what kind of consequences will that invite?

If profit is the primary motivation of an advanced AI, then what happens when it encounters a situation where profit comes at the cost of lives? There are already human-run companies that make those decision and people die because of them. An advanced AI will only make it many times worse.

Once an artificial intelligence system is as smart as a human, it’s going to be capable in ways we don’t expect and can’t control. If it’s ethics and goals aren’t aligned with us, then what’s to stop it from wiping humanity out in the name of profit?

It’s a distressing thought. It’s probably a thought that has crossed Ms. Gebru’s mind more than once. She may know how close or far we are to that point, but the fact that this is already a conflict should worry us all.

We’ve already become so numb to the greed and excesses of big business. Tech companies may conduct themselves as this team of future-building visionaries intent on making the world a better place, but the profit motive is still there. Like it or not, profit is still a hell of a motive.

Eventually, artificial intelligence will get to a point where it will either adopt our ethics or choose to formulate its own, which may or may not align with ours. When that happens, no amount of profit may be worth the risk.

Now, we’re still a ways off from an artificial intelligence system on that level, but it’s still quite possible that there are people alive today who will grow up to see it. When that time comes, we need to be damn sure these systems have solid ethical frameworks in place.

If they don’t, we really don’t stand a chance. We’re a society that still kills each other over what we think happens when we die without seeing the irony. Even a marginally advanced AI will have no issues wiping us out if we make doing so profitable.

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Vaccine Update: The Impact Of The Moderna Vaccine (Beyond COVID-19)

Sometimes, it takes a terrible global crisis to spurn huge leaps in technology. World War II was arguably the greatest crisis of the modern era, but it helps advance some of the greatest technological leaps in history. We can argue whether those advances were worth all the death and destruction, but there’s no denying that our world wouldn’t be the same without them.

The COVID-19 pandemic isn’t on the same level as World War II, but it is, by most measures, the greatest crisis the world has faced in the past 50 years. It hasn’t just caused hundreds of thousands of deaths and immeasurable amounts of suffering. It has completely disrupted this big, interconnected world that we’ve come to depend on.

We’ve all lost something in this pandemic. Beyond the loved ones who have perished, our entire sense of security and hope has been shattered. We now realize just how vulnerable we were and how inevitable this was. As bad as it is, there is some good coming out of it.

Usually, a crisis like this helps break down the barriers that divided us and hindered progress, technological or otherwise. Never before has the world been more united or engaged in a singular effort. Before 2020, we probably didn’t know much about vaccines or vaccine research. We just knew that Jenny McCarthy tried to be relevant again by protesting them.

That’s changing now. The global effort to create a vaccine for this terrible disease has been watched and agonized over for months. Most recently, we got a much-needed glimmer of hope from Pfizer, who reported that their vaccine is 90 percent effective. I celebrated this news like everyone else.

Then, we got an even greater glimmer of hope from the other vaccine front-runner by Moderna. Not only is their vaccine in the final phase of testing, like Pfizer. It’s even more effective and promises to be easier to store and distribute.

CNN: Moderna’s coronavirus vaccine is 94.5% effective, according to company data

The Moderna vaccine is 94.5% effective against coronavirus, according to early data released Monday by the company, making it the second vaccine in the United States to have a stunningly high success rate.

“These are obviously very exciting results,” said Dr. Anthony Fauci, the nation’s top infectious disease doctor. “It’s just as good as it gets — 94.5% is truly outstanding.”

Moderna heard its results on a call Sunday afternoon with members of the Data Safety and Monitoring Board, an independent panel analyzing Moderna’s clinical trial data.

This is objectively great news in a year when we’ve had precious little of it. These two vaccines may very well be the one-two punch we need to end the COVID-19 pandemic and return to some semblance of normalcy. I would still like to go to a movie theater or baseball game at some point in 2021. These vaccines may make that possible.

However, I’d like to take a moment to speculate beyond this terrible pandemic that has uprooted so many lives. I know that’s not easy to do when the crisis is still very relevant and inflicting plenty of suffering. I still think it’s worth attempting, if only to imagine the better world that emerges from this mess.

That’s because both these vaccines aren’t like your typical flu shots. For one, flu shots aren’t nearly as effective as what Pfizer and Moderna reported. According to the CDC, you’re average flu shot is between 40 and 60 percent effective. That’s still important because the flu can be deadly. Anything you do to reduce it can only further public health, in general.

The problem is the flu shot, and most vaccines like it, are based on old technology. At their most basic, they take a non-infectious or weakened strain of a pathogen and use it to amp up your body’s immunity. It’s crude, but it works. Literally nothing has saved more lives than vaccines.

The problem is that vaccines are notoriously hard to develop. They take a long time to test and an even longer time to approve. Until this pandemic, there just wasn’t much incentive to improve on that process. Now, after these past 8 months, the incentive couldn’t have been greater.

That’s what sped up the development of mRNA vaccines, the technology behind both Pfizer and Moderna. It was reported on as far back as 2018. While this technology isn’t completely new, it has never been developed beyond a certain point. There just wasn’t any incentive to do so. A global crisis changed that.

Very simply, an mRNA vaccine does one better on traditional vaccines by using RNA to develop immunity. It’s not as easy as it sounds. To develop that immunity, it has encode itself with just the right antigen. That way, the antibodies it creates can attack the desired pathogen.

In the case of COVID-19, the mRNA vaccine attacks the distinct spike protein the virus uses to attach to host cells. It’s like a missile targeting a specific individual in a large crowd by locking onto the distinct hat they wear.

This approach has the potential to be much more effective at generating immunity to a particular disease. Instead of trying to mimic a virus, it just gives the immune system the necessary software it needs to do the work. It could potentially revolutionize the way we treat and prevent diseases.

For years, certain viruses like the flu and HIV have confounded efforts to develop a vaccine. Beyond the problems I listed earlier with regards to testing, the difficulty of creating a particular immune response to a particular antigen is very difficult. These viruses mutate and change all the time. With COVID, vaccines do have an advantage because they have a distinct feature.

The challenge for future vaccines against future pandemics is quickly uncovering a particular antigen that the mRNA can be coded for. In theory, all you would have to do is find the one key antigen that’s common to every strain of the virus. While viruses like the flu are notoriously diverse, they can only change so much.

It’s akin to trying to identify an army of spies in a large crowd. They may all look different on the outside, but if they all have the same socks, then that’s what you code for. With some refinements, an mRNA vaccine can stop a pandemic in its tracks before it ever gets beyond a certain point.

That assumes we’ll continue to refine this technology after the COVID-19 pandemic has passed. I certainly hope that’s the case. This year has traumatized entire generations with how much pain and suffering it has inflicted. I sincerely hope that gives plenty of motivation to develop technology like this. That way, we never have to endure a disruption like this again.

To all those who helped develop this technology and these two vaccines, I hope you appreciate the impact you’ll make with this technology. The number of lives they could save is incalculable. Future generations may not remember your names, but they will be forever grateful for this wondrous gift you’ve given them.

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Filed under Current Events, futurism, health, technology, Uplifting Stories