It’s official. I got my second shot of the COVID-19 vaccine! As of now, I can count myself among those who are fully vaccinated against this terrible disease that has so ravaged the world. To say it’s a great feeling doesn’t do justice to all those who have endured hardship over the past year.
Once again, I cannot praise the brave nurses and doctors behind this effort enough. They are true heroes and, coming from a lifelong fan of superhero comics and movies, that’s saying something. This pandemic has been harder on you than most. Your efforts, your bravery, and your commitment to healing the sick is truly astonishing.
Like my first shot, this one was just as smooth. I showed up a few minutes early, stood in line for a bit, showed the nurse my vaccine card, and they did the rest. It was no worse than a flu shot. My arm was sore for a while, but other than that, I felt fine.
Now, I feel even better. I cannot overstate how big a relief it is that I’ve gotten this vaccine. It’s not just more peace of mind than I’ve had since early last year. Having been vaccinated, along with other friends and family, I can actually start planning things beyond this pandemic.
Last year, I couldn’t travel. In fact, I have not left my home county since October last year. I’m ready to get out again. I’m ready to visit friends, family, and beaches. I am so ready.
I missed out on a lot of great moments last year.
I don’t intend on missing out this year.
Once again, to the doctors, nurses, researchers, and scientists who helped develop this vaccine in record time, I sincerely thank you. On behalf of everyone who has lived through this once-in-a-generation pandemic, thank you from the bottom of our collective hearts.
Last year did a lot to crush my usually optimistic outlook on the future. I experienced a level of cynicism I haven’t felt since high school, a time when I only ever assumed things would get worse and rarely made an effort to change that. It was bad. Global pandemics have that effect on people.
I still made it a point to note when positive things actually happened, especially when it came to news of the vaccine. That marked the ultimate turning point. A vaccine was always going to be our best weapon in terms of ending the pandemic, regardless of what the anti-vaxx crowd says. The fact that we now have two vaccines at our disposal is genuinely encouraging.
Yes, I know the distribution of these vaccines has been a mess, to say the least.
Those are legitimate concerns. We should all be worried about how this will impact our ability to finally end this awful pandemic that has caused so much damage. At the same time, we should also be hopeful. Believe me, I’m trying.
That hope got another boost recently when it was announced that a third vaccine developed by Johnson & Johnson had completed its final round of trials. Having a third weapon against this virus can only help. In addition, this one has the advantage of being a one-shot vaccine, as opposed to the two required by Moderna and Pfizer.
While that’s good news for those who hate needles, there is a trade-off. According to the research reported by the media, the vaccine is effective. However, the numbers aren’t quite as promising as what we got with the first two. This is what CNN reported.
Johnson & Johnson’s Covid-19 single-shot vaccine was shown to be 66% effective in preventing moderate and severe disease in a global Phase 3 trial, but 85% effective against severe disease, the company announced Friday.
The vaccine was 72% effective against moderate and severe disease in the US, the company said.
It’s a striking difference from vaccines from Pfizer/BioNTech and Moderna, and it may give pause to people uncertain about which vaccine to get or when they can get one. The vaccines already on the market in the US are about 95% effective overall against symptomatic Covid-19, with perhaps even higher efficacy against severe cases.
But experts say the Johnson & Johnson vaccine will still be useful against the pandemic in the United States and around the world.
I know the numbers are the only thing that stands out in this piece. That seems to be the main sticking point for most reports about this virus.
Those numbers are still good. The 66% may not be as promising as the 90% promised by the other two, but that’s still more effective than a standard flu vaccine. On top of that, being a one-shot vaccine that can be easily stored in a typical refrigerator will help even more. It means more of this vaccine can get to people, especially in places with less-than-ideal health infrastructure.
This will definitely help in terms of ending or at least mitigating this pandemic. However, there’s one other critical point of data that’s worth highlighting with this vaccine. It’s in some of the reports, but it’s often difficult to discern, mostly because the media’s track record with reporting science is not that great.
For this vaccine, it’s boils down to certain degrees within the data. It’s true the Johnson & Johnson vaccine won’t give you the same protection you’d get from the other two. There’s a good chance that, even after getting this vaccine, you could still become very sick with COVID-19. However, and this is the key, it will help ensure that you don’t become severely ill and die.
To me, at least, that’s the most important result. Getting sick is one thing. Getting so sick that you die in a hospital bed is something else entirely. One is a bad flu. The other is debilitating illness. That alone makes this vaccine a critical tool in the effort to end this pandemic.
I admit that if I had a choice between the three, I would choose Moderna or Pfizer. I actually know someone who got the Pfizer vaccine and their experience gives me great assurance that it works as intended.
However, if those two were not available and all I could get was the Johnson & Johnson vaccine, I’d take it in a heartbeat. It could mean the difference between being sick and being deathly ill. In a pandemic, that’s the only difference that matters. To all the doctors, nurses, participants, and health care workers who were part of this effort, I sincerely thank you. A lot of lives will be saved because of this vaccine. That makes you true heroes in a world that badly needs them.
Some things really shouldn’t have to be said. They’re so obvious, both in terms of common sense and basic human decency, that nobody should have to be reminded in any capacity. If you have a functioning brain and a simple understanding of a situation, you have no excuse.
Sadly, there are some people in this world who are just a special kind of asshole.
They don’t care what makes sense or what’s generally decent. They’ll just find a way to serve themselves, even if it causes legitimate harm to others.
However, now that there are two vaccines available to end this pandemic, more assholes are being exposed in the most hypocritical way possible. Now, it should go without saying that, given the state of the pandemic, the first people who should get this treatment are the front line health care workers.
These people are the legitimate heroes of this pandemic. They need this vaccine. They deserve it. More lives will be saved because of them.
Even so, some people who are not front line health care workers are attempting to get this vaccine. Some are powerful people with powerful connections. Some are just well-connected, in general. Whatever their reason, if they’re not a front line health care worker, they’re still a special kind of asshole for cutting in line to get this vaccine.
I can’t be subtle or tactful about this.
I can’t be polite about it, either.
I’m just going to say what I feel as someone who has witnessed the damage and suffering that this pandemic has caused like so many others. It shouldn’t have to be said, but I’ll say it anyways.
If you’re a politician who uses their power and influence to get the vaccine before a single front line health care worker, you’re an asshole.
If you’re a rich, well-connected business type who uses their money and connection to get the vaccine before a single front line health care worker, you’re an asshole.
If you’re the friend or spouse of a billionaire or politician who uses that friendship to get the vaccine before a single front line health care worker, you’re an asshole.
If you’re someone who downplayed the pandemic or scoffed at basic health guidelines when it began and still attempt to get the vaccine, you’re an asshole.
If you’re an anti-evolution religious zealot who encouraged congregates to ignore the advice of doctors during the pandemic and still try to get the vaccine, you’re an asshole.
If you’re a just liar, cheater, or con-artist who uses those skills to get the vaccine before a single front line health care worker, you’re an asshole of the highest order.
In essence, if you’re trying to jump ahead in the line to get this vaccine for any reason, even if you’re among those who didn’t take the pandemic seriously in the beginning, you are an asshole in the highest order. You are just one of the reasons why people lose faith in humanity and the future.
I would tell these people to knock it off, apologize, or show some basic human decency, but I have a feeling they’ll either ignore me or just make an excuse. I doubt those people would ever read this. I still think this is worth saying, if only to share that angry sentiment that many feel when they hear about people cutting in line to get this life-saving treatment.
The world is still in a precarious place right now. The pandemic isn’t over. There’s still a lot of work to be done and, as has been the case since the beginning, the front line health care workers who have been nothing short of superhuman, will bear the brunt of it. Anyone who cuts in front of them to get this treatment deserves nothing but the utmost scorn.
We will eventually emerge from this. Hopefully, there will come a point in 2021 where we can definitively say that this horrible pandemic is over. However, even after that fateful moment, let’s not forget about the assholes who did everything to help themselves when others were suffering.
They’ll still be assholes.
They’ll keep being assholes, no matter what the state of the world.
We can’t always avoid them, but we can expose them for the level asshole they are.
It’s almost over. I’m sure I’m not the only one thinking that with each passing day.
This historically horrible year is almost over. We’re in the home stretch with the holidays approaching. A new year is almost upon us and the bar for improvement for 2021 is laughably low compared to previous years.
The reason there’s hope now is we actually have a working vaccine. Thanks to the heroic efforts of scientists, doctors, and those who volunteered to test this unproven treatment, the key to ending this pandemic is upon us.
These aren’t folk remedies or something some shady health guru is trying to pawn for a quick buck. Contrary to what anti-vaxxers may claim, these vaccines will actually protect people. As of this writing, it’s being distributed to front line care workers and vulnerable populations.
Just this past week, the first individuals received the vaccine. It started with a British woman in Coventry. It continued with an ICU nurse in New York City. CNN even captured it in a live video feed.
A critical care nurse was the first person in New York and among the first people in the United States to get a shot of the coronavirus vaccine authorized by the US Food and Drug Administration.
Sandra Lindsay, an ICU nurse at Long Island Jewish Medical Center in Queens, New York City, was administered the vaccine during a live video event at about 9:20 a.m. ET on Monday.
Dr. Michelle Chester, the corporate director of employee health services at Northwell Health, delivered the shot.
“She has a good touch, and it didn’t feel any different than taking any other vaccine,” Lindsay said immediately afterward.
This isn’t just a turning point in the fight against a deadly disease. This is something we should celebrate. Moreover, I believe this is the kind of celebrating we should learn from.
I admit I’ve celebrated some less-than-important things in my life. Hell, I celebrated the day when comics started coming out digitally the same day they came out in shops. I treated that like I won the Super Bowl.
People celebrate all sorts of events that they believe to be the most important thing in the world. Whether it’s their team winning a championship or a movie grossing $2 billion at the box office, we all have a different bar for what warrants celebrating.
For just once, let’s all re-think where we raise that bar. Let’s also let this be a prime example of something that’s truly worth celebrating and praising.
Make no mistake. Creating this vaccine this quickly is a remarkable achievement. We’ve endured pandemics in the past. Some of those pandemics have killed far more people. This disease could’ve definitely killed more. If we didn’t have this vaccine, or even if we had to wait a year to get it, thousands more would’ve died.
Now, going into 2021, countless lives will be saved because of this. It’s a testament to the power of science, hard work, and human ingenuity. It’s as heroic as we can be without the aid of superpowers or magic wands. As someone who loves superhero media, I say that’s a beautiful thing indeed. So, let’s all take a moment to appreciate and celebrate this achievement. I also fully intend to get this vaccine, once it’s available. When that day comes, I’ll gladly share that moment and encourage others to do the same.
Sometimes, it takes a terrible global crisis to spurn huge leaps in technology. World War II was arguably the greatest crisis of the modern era, but it helps advance some of the greatest technological leaps in history. We can argue whether those advances were worth all the death and destruction, but there’s no denying that our world wouldn’t be the same without them.
The COVID-19 pandemic isn’t on the same level as World War II, but it is, by most measures, the greatest crisis the world has faced in the past 50 years. It hasn’t just caused hundreds of thousands of deaths and immeasurable amounts of suffering. It has completely disrupted this big, interconnected world that we’ve come to depend on.
We’ve all lost something in this pandemic. Beyond the loved ones who have perished, our entire sense of security and hope has been shattered. We now realize just how vulnerable we were and how inevitable this was. As bad as it is, there is some good coming out of it.
Usually, a crisis like this helps break down the barriers that divided us and hindered progress, technological or otherwise. Never before has the world been more united or engaged in a singular effort. Before 2020, we probably didn’t know much about vaccines or vaccine research. We just knew that Jenny McCarthy tried to be relevant again by protesting them.
Then, we got an even greater glimmer of hope from the other vaccine front-runner by Moderna. Not only is their vaccine in the final phase of testing, like Pfizer. It’s even more effective and promises to be easier to store and distribute.
The Moderna vaccine is 94.5% effective against coronavirus, according to early data released Monday by the company, making it the second vaccine in the United States to have a stunningly high success rate.
“These are obviously very exciting results,” said Dr. Anthony Fauci, the nation’s top infectious disease doctor. “It’s just as good as it gets — 94.5% is truly outstanding.”
Moderna heard its results on a call Sunday afternoon with members of the Data Safety and Monitoring Board, an independent panel analyzing Moderna’s clinical trial data.
This is objectively great news in a year when we’ve had precious little of it. These two vaccines may very well be the one-two punch we need to end the COVID-19 pandemic and return to some semblance of normalcy. I would still like to go to a movie theater or baseball game at some point in 2021. These vaccines may make that possible.
However, I’d like to take a moment to speculate beyond this terrible pandemic that has uprooted so many lives. I know that’s not easy to do when the crisis is still very relevant and inflicting plenty of suffering. I still think it’s worth attempting, if only to imagine the better world that emerges from this mess.
That’s because both these vaccines aren’t like your typical flu shots. For one, flu shots aren’t nearly as effective as what Pfizer and Moderna reported. According to the CDC, you’re average flu shot is between 40 and 60 percent effective. That’s still important because the flu can be deadly. Anything you do to reduce it can only further public health, in general.
The problem is that vaccines are notoriously hard to develop. They take a long time to test and an even longer time to approve. Until this pandemic, there just wasn’t much incentive to improve on that process. Now, after these past 8 months, the incentive couldn’t have been greater.
That’s what sped up the development of mRNA vaccines, the technology behind both Pfizer and Moderna. It was reported on as far back as 2018. While this technology isn’t completely new, it has never been developed beyond a certain point. There just wasn’t any incentive to do so. A global crisis changed that.
Very simply, an mRNA vaccine does one better on traditional vaccines by using RNA to develop immunity. It’s not as easy as it sounds. To develop that immunity, it has encode itself with just the right antigen. That way, the antibodies it creates can attack the desired pathogen.
In the case of COVID-19, the mRNA vaccine attacks the distinct spike protein the virus uses to attach to host cells. It’s like a missile targeting a specific individual in a large crowd by locking onto the distinct hat they wear.
This approach has the potential to be much more effective at generating immunity to a particular disease. Instead of trying to mimic a virus, it just gives the immune system the necessary software it needs to do the work. It could potentially revolutionize the way we treat and prevent diseases.
For years, certain viruses like the flu and HIV have confounded efforts to develop a vaccine. Beyond the problems I listed earlier with regards to testing, the difficulty of creating a particular immune response to a particular antigen is very difficult. These viruses mutate and change all the time. With COVID, vaccines do have an advantage because they have a distinct feature.
The challenge for future vaccines against future pandemics is quickly uncovering a particular antigen that the mRNA can be coded for. In theory, all you would have to do is find the one key antigen that’s common to every strain of the virus. While viruses like the flu are notoriously diverse, they can only change so much.
It’s akin to trying to identify an army of spies in a large crowd. They may all look different on the outside, but if they all have the same socks, then that’s what you code for. With some refinements, an mRNA vaccine can stop a pandemic in its tracks before it ever gets beyond a certain point.
That assumes we’ll continue to refine this technology after the COVID-19 pandemic has passed. I certainly hope that’s the case. This year has traumatized entire generations with how much pain and suffering it has inflicted. I sincerely hope that gives plenty of motivation to develop technology like this. That way, we never have to endure a disruption like this again.
To all those who helped develop this technology and these two vaccines, I hope you appreciate the impact you’ll make with this technology. The number of lives they could save is incalculable. Future generations may not remember your names, but they will be forever grateful for this wondrous gift you’ve given them.
In general, I’m a pretty optimistic person. I try to focus on the positives, even when I’m surrounded by a lot of negatives. It’s part of my personality. Granted, I wasn’t always like that. As a teenager, I was a pretty miserable, jaded, self-loathing cynic. There’s a long story behind that, but it’s not important right now
The reason I make that disclaimer is because the past few months have killed my sense of optimism. Actually, that’s an understatement. The impact of this massive global pandemic has taken my optimism, shot it five times with a shotgun, and ran it over eight times with a fully loaded pickup truck. My optimism is dead. It will be for the foreseeable future. That’s what this pandemic has done.
At this point, I question the sanity of anyone who has clung to any sense of optimism. Thousands of people are dead. Infections are in the millions. Things are getting worse every day. That’s not an opinion. That’s just basic goddamn math.
Now, I’m not trying to turn everyone into a pessimist, nor am I trying to crush everyone’s hopes. The point I want to make here is that there are just some things that hope cannot help, no matter how many inspirational quotes you read. Yes, hope and optimism can go a long way in many fields. A global pandemic just isn’t one of them.
To that point, I want to highlight the recent “optimism” surrounding vaccine research. I admit I too have been following this closely, too. How can you not? Even a cynic would agree. The best way to end this pandemic and get our lives back is with a vaccine. That’s somewhat distressing, given all the negative press vaccines had leading up to this moment.
At the same time, it’s remarkable how much the world has united behind this effort. I can’t remember a time when so many countries and so many organizations were this unified in their effort to achieve something. I want to find hope in that, but there are still a few intractable problem. This time, it has to do with both math and physics.
Making a vaccine is hard. There’s just no way around it. Even if you know the exact molecular sequence, producing it on a mass scale and distributing it to a large number of people is also difficult. It’s not a matter of will. It’s a matter of resources and logistics, the likes of which can’t be solved overnight or even within a year.
For that reason, when you see a positive story about a vaccine for COVID-19, you should be very pessimistic. Just look at this recent story from the Associated Press regarding Moderna’s vaccine research.
There’s no guarantee but the government hopes to have results around the end of the year — record-setting speed for developing a vaccine.
The vaccine requires two doses, a month apart.
There were no serious side effects. But more than half the study participants reported flu-like reactions to the shots that aren’t uncommon with other vaccines — fatigue, headache, chills, fever and pain at the injection site. For three participants given the highest dose, those reactions were more severe; that dose isn’t being pursued.
Some of those reactions are similar to coronavirus symptoms but they’re temporary, lasting about a day and occur right after vaccination, researchers noted.
“Small price to pay for protection against COVID,” said Dr. William Schaffner of Vanderbilt University Medical Center, a vaccine expert who wasn’t involved with the study.
He called the early results “a good first step,” and is optimistic that final testing could deliver answers about whether it’s really safe and effective by the beginning of next year.
On the surface, it looks rosy. It hints that a vaccine is getting closer. It may even arrive at the end of the year. They’re even saying that research is moving at record speed. It all sounds so great.
Don’t get your hopes up.
Don’t expect this pandemic to be over by Christmas, either.
Notice that I bolded the phrase “a good first step.” Also, note how few details about the research are actually listed or linked to. It just notes how many people were involved and how many will be utilized in the next step. That’s both a sign and a red flag.
It’s a common problem whenever the media tries to report on science. Actual scientific research, namely the kind reported in journals, is not the kind of thing you can fit into a simple news blurb. You can’t fit it in an article, let alone a tweet. Most scientific research, especially of the medical variety, involves a lot of numbers, intimate details, and chemical constructs that most people aren’t equipped to understand.
It’s not that the news media has to dumb it down for us, the public. It just can only report on the broadest details. Those details often include the various complications and shortcomings of the research. Make no mistake. Those complications are there. If they weren’t, then the scientific research wouldn’t be necessary. It’s why becoming a doctor is so difficult and laborious.
I don’t doubt for a second that most of these doctors want to end this pandemic. Some are probably hopeful that they’re close. However, you can’t be a good doctor without sticking to rigorous science. Breakthroughs don’t happen all at once. Those light-bulb moments we see in movies and TV shows aren’t even close to what happens in real life.
In real life, medical breakthroughs still take years if not decades. The sheer complexity of disease and our methods for treating it preclude easy fixes to big problems. In terms of problems, pandemics are as big as they come. If ending it required only one breakthrough, it would’ve been found by now and thousands of lives wouldn’t have been lost.
That’s why you should never look at vaccine news in terms of a breakthrough. Even headlines that inspire hope in this field can only ever tell part of the story. Unfortunately, science is hard and so is creating effective medicine. You can’t rush it. You can’t encourage it. It’s at the mercy of hard limits that you can’t bullshit your way around. That’s what makes it hard. It’s also why it works.
Remember that the next time you see headlines about the prospect of vaccine research. Don’t assume it’s going to finish tomorrow. Don’t assume a miracle will speed it up. That’s not how science works and that’s not how this pandemic will end. For now, the best we can do is endure, brace ourselves, and retain our sanity until things eventually do change for the better.