Tag Archives: Moderna

June 21, 2021 · 9:19 am

Dear Vaccine Conspiracy Theorists: You’re Killing People (And Making A Fool Of Yourself)

Wednesday, March 17th 2021: JJ McCartney LIVE on St. Patrick's Day 3-5pmET – JJMcCartney 24/7 – The Re-Union Station

In general, I try to respect the sincerely held beliefs of others. It’s something I hope most decent human beings can agree upon. Mocking, belittling, or denigrating someone else’s beliefs isn’t just bound to cause conflict. It’s just a dick move.

I say that as someone who has criticized organized religion many times before. Within those criticism, though, I make it a point to say that I try to respect those who are sincere in their beliefs. I’ve no desire to mock them or make them feel lesser for believing what they belief.

All that being said, I draw a clear line when those beliefs get people killed.

This brings me to vaccines and the conspiracy theorists who love whining about them. These are people whose beliefs are hard to respect in any context. They’re not just skeptical about the efficacy of vaccines. They go out of their way to protest their use, even during a global pandemic that has killed millions.

I’m sorry, but I just can’t respect that. I don’t care if it’s for religious or non-religious reasons. This sort of thing is killing people. That’s objectively bad.

Now, I predicted last year that religious zealots would be among those who refuse to take vaccines and go out of their way to denigrate scientists. Unfortunately, that prediction proved distressingly accurate.

However, what I didn’t predict was how many self-professed “skeptics” would protest vaccines for non-religious reasons. I knew it was going to get absurd. I just didn’t know it was going to get “vaccines are making people magnets” absurd.

Seriously, I wish I were making that up. That’s a real testimony from a registered nurse, of all people, during an Ohio public hearing. Here’s the story from the Huffington Post. Be warned, though. Your faith in humanity will be shaken.

Huff Post: Nurse’s Attempt To Prove Vaccines Make People Magnetic Hilariously Backfires

An anti-vaccine Ohio nurse attempted on Tuesday to prove that COVID-19 vaccines make people magnetic, but ― to use a gymnastics term ― she failed to stick the landing.

Registered nurse Joanna Overholt, testifying before the Ohio House health committee about what she said were potential coronavirus vaccine dangers, tried to use her own body as proof.

Overholt said she heard during lunch that vaccines cause magnetism in humans, so she decided to prove her point on herself by attempting to show how a bobby pin and a key would stick to her exposed skin.

Spoiler alert: It didn’t go well.

Now, I don’t know this woman’s full story. I have no idea what’s going on in her life or what led her to belief something this absurd. I’m fairly certain she didn’t just wake up one day and decide to believe bullshit conspiracy theories about vaccines.

Whatever her story, it doesn’t change the implications or the consequences. What she’s promoting isn’t just wrong or absurd. It’s legitimately harmful. On top of that, we’re still dealing with a pandemic and rhetoric like this is going to get people killed.

That’s the main takeaway I glean every time I see stories like this. That’s what sets them apart from other absurd conspiracy theories. Believing there are alien bodies in Area 51 or that the moon is made of cheese doesn’t directly harm anyone. Just being ignorant of certain facts is also forgivable. The internet is full of dumb falsehoods these days.

However, there are some facts that just aren’t in dispute. Chief among them is the demonstrable fact that vaccines save lives. The fact that nobody has died from smallpox in five decades is proof enough of that. In fact, few advances have ever saved as many lives as vaccines. The vaccines for COVID-19 are only adding to that total.

Unfortunately, these anti-vaxx conspiracy theorists are only fueling a sense of vaccine hesitancy that was always going to be an issue. Even before the age of the internet or modern religion, there has always been a skepticism about scientific advancements. This is just making it worse and getting people killed.

It’s one thing to make yourself look foolish in public in a manner that’s recorded and spread throughout the internet. That usually doesn’t have major consequences beyond making certain people internet celebrities for all the wrong reasons. It’s quite another to be foolish in a manner that undermines public health and leads to undue suffering.

There’s just no getting around it. Lower vaccination rates mean more disease. More disease means more suffering. In this case, it’s not a minor inconvenience. It’s potentially fatal. I feel like that last detail is worth emphasizing.

The problem is that those pushing anti-vaccine conspiracies don’t see that detail, either by ignorance or by choice. They may, in their heart of hearts, believe they’re saving lives by preventing people from getting vaccines. However, basic biology and math say otherwise. The data is not in dispute.

These beliefs are killing people.

The people who push these beliefs are responsible for propagating that suffering.

These beliefs do not deserve respect.

Consider this both a plea and an angry rant of sorts. If you are pushing these conspiracy theories, you’re not just a misguided fool. You’re going to get people killed. After last year, we dealt with enough death. Please don’t add to it.

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December 28, 2020 · 10:19 am

PSA: If You Cut In Line To Get The COVID-19 Vaccine, You’re An Asshole

Some things really shouldn’t have to be said. They’re so obvious, both in terms of common sense and basic human decency, that nobody should have to be reminded in any capacity. If you have a functioning brain and a simple understanding of a situation, you have no excuse.

Sadly, there are some people in this world who are just a special kind of asshole.

They don’t care what makes sense or what’s generally decent. They’ll just find a way to serve themselves, even if it causes legitimate harm to others.

This brings me to the assholes that the ongoing global pandemic has exposed. Now, this pandemic has already exposed plenty of assholes of a certain variety. The people who downplayed the pandemic and refused to take precautions are already deplorable human beings by any measure.

However, now that there are two vaccines available to end this pandemic, more assholes are being exposed in the most hypocritical way possible. Now, it should go without saying that, given the state of the pandemic, the first people who should get this treatment are the front line health care workers.

These people are the legitimate heroes of this pandemic. They need this vaccine. They deserve it. More lives will be saved because of them.

Even so, some people who are not front line health care workers are attempting to get this vaccine. Some are powerful people with powerful connections. Some are just well-connected, in general. Whatever their reason, if they’re not a front line health care worker, they’re still a special kind of asshole for cutting in line to get this vaccine.

I can’t be subtle or tactful about this.

I can’t be polite about it, either.

I’m just going to say what I feel as someone who has witnessed the damage and suffering that this pandemic has caused like so many others. It shouldn’t have to be said, but I’ll say it anyways.

If you’re a politician who uses their power and influence to get the vaccine before a single front line health care worker, you’re an asshole.

If you’re a rich, well-connected business type who uses their money and connection to get the vaccine before a single front line health care worker, you’re an asshole.

If you’re the friend or spouse of a billionaire or politician who uses that friendship to get the vaccine before a single front line health care worker, you’re an asshole.

If you’re someone who downplayed the pandemic or scoffed at basic health guidelines when it began and still attempt to get the vaccine, you’re an asshole.

If you’re an anti-evolution religious zealot who encouraged congregates to ignore the advice of doctors during the pandemic and still try to get the vaccine, you’re an asshole.

If you’re a just liar, cheater, or con-artist who uses those skills to get the vaccine before a single front line health care worker, you’re an asshole of the highest order.

In essence, if you’re trying to jump ahead in the line to get this vaccine for any reason, even if you’re among those who didn’t take the pandemic seriously in the beginning, you are an asshole in the highest order. You are just one of the reasons why people lose faith in humanity and the future.

I would tell these people to knock it off, apologize, or show some basic human decency, but I have a feeling they’ll either ignore me or just make an excuse. I doubt those people would ever read this. I still think this is worth saying, if only to share that angry sentiment that many feel when they hear about people cutting in line to get this life-saving treatment.

The world is still in a precarious place right now. The pandemic isn’t over. There’s still a lot of work to be done and, as has been the case since the beginning, the front line health care workers who have been nothing short of superhuman, will bear the brunt of it. Anyone who cuts in front of them to get this treatment deserves nothing but the utmost scorn.

We will eventually emerge from this. Hopefully, there will come a point in 2021 where we can definitively say that this horrible pandemic is over. However, even after that fateful moment, let’s not forget about the assholes who did everything to help themselves when others were suffering.

They’ll still be assholes.

They’ll keep being assholes, no matter what the state of the world.

We can’t always avoid them, but we can expose them for the level asshole they are.

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November 20, 2020 · 5:58 am

Vaccine Update: The Impact Of The Moderna Vaccine (Beyond COVID-19)

Sometimes, it takes a terrible global crisis to spurn huge leaps in technology. World War II was arguably the greatest crisis of the modern era, but it helps advance some of the greatest technological leaps in history. We can argue whether those advances were worth all the death and destruction, but there’s no denying that our world wouldn’t be the same without them.

The COVID-19 pandemic isn’t on the same level as World War II, but it is, by most measures, the greatest crisis the world has faced in the past 50 years. It hasn’t just caused hundreds of thousands of deaths and immeasurable amounts of suffering. It has completely disrupted this big, interconnected world that we’ve come to depend on.

We’ve all lost something in this pandemic. Beyond the loved ones who have perished, our entire sense of security and hope has been shattered. We now realize just how vulnerable we were and how inevitable this was. As bad as it is, there is some good coming out of it.

Usually, a crisis like this helps break down the barriers that divided us and hindered progress, technological or otherwise. Never before has the world been more united or engaged in a singular effort. Before 2020, we probably didn’t know much about vaccines or vaccine research. We just knew that Jenny McCarthy tried to be relevant again by protesting them.

That’s changing now. The global effort to create a vaccine for this terrible disease has been watched and agonized over for months. Most recently, we got a much-needed glimmer of hope from Pfizer, who reported that their vaccine is 90 percent effective. I celebrated this news like everyone else.

Then, we got an even greater glimmer of hope from the other vaccine front-runner by Moderna. Not only is their vaccine in the final phase of testing, like Pfizer. It’s even more effective and promises to be easier to store and distribute.

CNN: Moderna’s coronavirus vaccine is 94.5% effective, according to company data

The Moderna vaccine is 94.5% effective against coronavirus, according to early data released Monday by the company, making it the second vaccine in the United States to have a stunningly high success rate.

“These are obviously very exciting results,” said Dr. Anthony Fauci, the nation’s top infectious disease doctor. “It’s just as good as it gets — 94.5% is truly outstanding.”

Moderna heard its results on a call Sunday afternoon with members of the Data Safety and Monitoring Board, an independent panel analyzing Moderna’s clinical trial data.

This is objectively great news in a year when we’ve had precious little of it. These two vaccines may very well be the one-two punch we need to end the COVID-19 pandemic and return to some semblance of normalcy. I would still like to go to a movie theater or baseball game at some point in 2021. These vaccines may make that possible.

However, I’d like to take a moment to speculate beyond this terrible pandemic that has uprooted so many lives. I know that’s not easy to do when the crisis is still very relevant and inflicting plenty of suffering. I still think it’s worth attempting, if only to imagine the better world that emerges from this mess.

That’s because both these vaccines aren’t like your typical flu shots. For one, flu shots aren’t nearly as effective as what Pfizer and Moderna reported. According to the CDC, you’re average flu shot is between 40 and 60 percent effective. That’s still important because the flu can be deadly. Anything you do to reduce it can only further public health, in general.

The problem is the flu shot, and most vaccines like it, are based on old technology. At their most basic, they take a non-infectious or weakened strain of a pathogen and use it to amp up your body’s immunity. It’s crude, but it works. Literally nothing has saved more lives than vaccines.

The problem is that vaccines are notoriously hard to develop. They take a long time to test and an even longer time to approve. Until this pandemic, there just wasn’t much incentive to improve on that process. Now, after these past 8 months, the incentive couldn’t have been greater.

That’s what sped up the development of mRNA vaccines, the technology behind both Pfizer and Moderna. It was reported on as far back as 2018. While this technology isn’t completely new, it has never been developed beyond a certain point. There just wasn’t any incentive to do so. A global crisis changed that.

Very simply, an mRNA vaccine does one better on traditional vaccines by using RNA to develop immunity. It’s not as easy as it sounds. To develop that immunity, it has encode itself with just the right antigen. That way, the antibodies it creates can attack the desired pathogen.

In the case of COVID-19, the mRNA vaccine attacks the distinct spike protein the virus uses to attach to host cells. It’s like a missile targeting a specific individual in a large crowd by locking onto the distinct hat they wear.

This approach has the potential to be much more effective at generating immunity to a particular disease. Instead of trying to mimic a virus, it just gives the immune system the necessary software it needs to do the work. It could potentially revolutionize the way we treat and prevent diseases.

For years, certain viruses like the flu and HIV have confounded efforts to develop a vaccine. Beyond the problems I listed earlier with regards to testing, the difficulty of creating a particular immune response to a particular antigen is very difficult. These viruses mutate and change all the time. With COVID, vaccines do have an advantage because they have a distinct feature.

The challenge for future vaccines against future pandemics is quickly uncovering a particular antigen that the mRNA can be coded for. In theory, all you would have to do is find the one key antigen that’s common to every strain of the virus. While viruses like the flu are notoriously diverse, they can only change so much.

It’s akin to trying to identify an army of spies in a large crowd. They may all look different on the outside, but if they all have the same socks, then that’s what you code for. With some refinements, an mRNA vaccine can stop a pandemic in its tracks before it ever gets beyond a certain point.

That assumes we’ll continue to refine this technology after the COVID-19 pandemic has passed. I certainly hope that’s the case. This year has traumatized entire generations with how much pain and suffering it has inflicted. I sincerely hope that gives plenty of motivation to develop technology like this. That way, we never have to endure a disruption like this again.

To all those who helped develop this technology and these two vaccines, I hope you appreciate the impact you’ll make with this technology. The number of lives they could save is incalculable. Future generations may not remember your names, but they will be forever grateful for this wondrous gift you’ve given them.

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July 21, 2020 · 5:58 am

Why You Should Be Pessimistic About Optimistic News On Vaccines

In general, I’m a pretty optimistic person. I try to focus on the positives, even when I’m surrounded by a lot of negatives. It’s part of my personality. Granted, I wasn’t always like that. As a teenager, I was a pretty miserable, jaded, self-loathing cynic. There’s a long story behind that, but it’s not important right now

The reason I make that disclaimer is because the past few months have killed my sense of optimism. Actually, that’s an understatement. The impact of this massive global pandemic has taken my optimism, shot it five times with a shotgun, and ran it over eight times with a fully loaded pickup truck. My optimism is dead. It will be for the foreseeable future. That’s what this pandemic has done.

At this point, I question the sanity of anyone who has clung to any sense of optimism. Thousands of people are dead. Infections are in the millions. Things are getting worse every day. That’s not an opinion. That’s just basic goddamn math.

Now, I’m not trying to turn everyone into a pessimist, nor am I trying to crush everyone’s hopes. The point I want to make here is that there are just some things that hope cannot help, no matter how many inspirational quotes you read. Yes, hope and optimism can go a long way in many fields. A global pandemic just isn’t one of them.

To that point, I want to highlight the recent “optimism” surrounding vaccine research. I admit I too have been following this closely, too. How can you not? Even a cynic would agree. The best way to end this pandemic and get our lives back is with a vaccine. That’s somewhat distressing, given all the negative press vaccines had leading up to this moment.

At the same time, it’s remarkable how much the world has united behind this effort. I can’t remember a time when so many countries and so many organizations were this unified in their effort to achieve something. I want to find hope in that, but there are still a few intractable problem. This time, it has to do with both math and physics.

Making a vaccine is hard. There’s just no way around it. Even if you know the exact molecular sequence, producing it on a mass scale and distributing it to a large number of people is also difficult. It’s not a matter of will. It’s a matter of resources and logistics, the likes of which can’t be solved overnight or even within a year.

For that reason, when you see a positive story about a vaccine for COVID-19, you should be very pessimistic. Just look at this recent story from the Associated Press regarding Moderna’s vaccine research.

AP: First COVID-19 vaccine tested in US poised for final testing

There’s no guarantee but the government hopes to have results around the end of the year — record-setting speed for developing a vaccine.

The vaccine requires two doses, a month apart.

There were no serious side effects. But more than half the study participants reported flu-like reactions to the shots that aren’t uncommon with other vaccines — fatigue, headache, chills, fever and pain at the injection site. For three participants given the highest dose, those reactions were more severe; that dose isn’t being pursued.

Some of those reactions are similar to coronavirus symptoms but they’re temporary, lasting about a day and occur right after vaccination, researchers noted.

“Small price to pay for protection against COVID,” said Dr. William Schaffner of Vanderbilt University Medical Center, a vaccine expert who wasn’t involved with the study.

He called the early results “a good first step,” and is optimistic that final testing could deliver answers about whether it’s really safe and effective by the beginning of next year.

On the surface, it looks rosy. It hints that a vaccine is getting closer. It may even arrive at the end of the year. They’re even saying that research is moving at record speed. It all sounds so great.

Don’t get your hopes up.

Don’t expect this pandemic to be over by Christmas, either.

Notice that I bolded the phrase “a good first step.” Also, note how few details about the research are actually listed or linked to. It just notes how many people were involved and how many will be utilized in the next step. That’s both a sign and a red flag.

It’s a common problem whenever the media tries to report on science. Actual scientific research, namely the kind reported in journals, is not the kind of thing you can fit into a simple news blurb. You can’t fit it in an article, let alone a tweet. Most scientific research, especially of the medical variety, involves a lot of numbers, intimate details, and chemical constructs that most people aren’t equipped to understand.

It’s not that the news media has to dumb it down for us, the public. It just can only report on the broadest details. Those details often include the various complications and shortcomings of the research. Make no mistake. Those complications are there. If they weren’t, then the scientific research wouldn’t be necessary. It’s why becoming a doctor is so difficult and laborious.

I don’t doubt for a second that most of these doctors want to end this pandemic. Some are probably hopeful that they’re close. However, you can’t be a good doctor without sticking to rigorous science. Breakthroughs don’t happen all at once. Those light-bulb moments we see in movies and TV shows aren’t even close to what happens in real life.

In real life, medical breakthroughs still take years if not decades. The sheer complexity of disease and our methods for treating it preclude easy fixes to big problems. In terms of problems, pandemics are as big as they come. If ending it required only one breakthrough, it would’ve been found by now and thousands of lives wouldn’t have been lost.

That’s why you should never look at vaccine news in terms of a breakthrough. Even headlines that inspire hope in this field can only ever tell part of the story. Unfortunately, science is hard and so is creating effective medicine. You can’t rush it. You can’t encourage it. It’s at the mercy of hard limits that you can’t bullshit your way around. That’s what makes it hard. It’s also why it works.

Remember that the next time you see headlines about the prospect of vaccine research. Don’t assume it’s going to finish tomorrow. Don’t assume a miracle will speed it up. That’s not how science works and that’s not how this pandemic will end. For now, the best we can do is endure, brace ourselves, and retain our sanity until things eventually do change for the better.

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